The company said the mixed-use development will help transform one of the key gateways into the Hampshire city.
Located near to Southampton Central Station, the scheme comprises the refurbishment of existing 2,090m² office space blended with a number of architecturally striking new build structures, including the creation of 13,700m² of residential, 3,700m² of new office space and approximately 900m² of retail space.
The outline planning approval is for a 20-storey residential tower, containing 110 apartments, as well as commercial facilities at the ground and lower ground floor levels. Adjoining, will be an 11-storey hotel with 225 bedrooms.
Detailed planning permission was also granted to enhance the office facilities on the site. The approved plans will allow for the provision of new Grade A office space to be built, incorporating a roof terrace for use by office tenants, as well as the refurbishment of existing office buildings.
The planning application for the redevelopment of Nelson Gate was submitted after a consultation event earlier this year which gained strong support from residents and local stakeholders.
The scheme has been designed by Ellis Williams Architects and planning consultants WYG.